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Inter-ictal activity recorded from the cortico-hippocampal circuit of acute brain slices of rat.

This dataset shows activity propagation of inter-ictal events induced by perfusion of 4AP. Data kindly provided by Cinvestav.

Recording of spontaneous activity from the ganglion cell layer in a knockout mouse used as a model of a dystrophic retina.
This dataset shows strong spontaneous bursting and propagation of the activity along axons converging towards the optic disc. Data kindly provided by The Institute of Neuroscience (ION).

The BioCAM Driver API provides the necessary toolset to drive the BioCAM device and to interface with your biological cultures via the 3Brain BioSPU microchip. It enables performing closed-loop experiments, by providing the experimenter the ability to achieve a latency time of ~1.5ms.‍

The API is built on .NET Framework 4.7. and is compatible with Windows 10 or 11. The current version of the API, v. 2.2, supports the BioCAM DupleX with firmware 1.7.0.8 or higher. The API can be usedin C++, Java, Python, etc. by using a proper wrapper (not provided).

BrainWave 5 provides advanced and AI-driven tools for managing, analysing and extracting information from both single-well and multiwell systems. The latest software version is compatible with Windows 10 and 11.

BrainWave 5 is compatible with BioCAM DupleX and HyperCAM Alpha.

Spontaneous activity of a dissociated hippocampal cultures at 32DIVs, seeded at a nominal concentration of 1000 cells/ul.

This dataset shows spontaneous activity organized in synchronous bursts that mainly initiate from the bottom left and bottom right area of the array. Strong single spike events and short trains of activity can be easily identified. Data kindly provided by Nets3 Lab (IIT).

Spontaneous activity of an immature dissociated hippocampal cultures at 11DIVs.

Despite the young age, the culture exhibits a sustained activity with strong spike events on many electrodes. Sporadic network bursts show the onset of synchronous activity.  

Long Term Potentiation experiment on the CA1 region in a cortico-hippocampal slice of a mouse. The LTP protocol has been executed by using EVOS a software add-on of Brainwave 4. Sub-areas of the CA1 region show different potentiation profiles. Data kindly provided by Prof. Balschun KU Leuven.