Multi-well system: A new frontier in functional imaging

Name: HyperCAM Alpha
Brand: 3Brain AG
Availability: InStock

The 6-well CorePlate™ -powered platform designed for both cell culture and tissue preparations

Overview

Your companion in functional cell screening

Thanks to the CorePlate™ technology, HyperCAM Alpha delivers high resolution functional screening platform in a multi-well plate format.
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The controlled environment allows label-free kinetic in vitro assays. The large sensing area of the per-well integrated microchip provides room for measuring either cell cultures, brain slices or brain organoids.
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Alpha is equipped with the latest generation of FPGA accelerators to manage real-time high-resolution data from up to 13 824 (2 304 per well) simultaneously recorded electrodes.
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Complex operations are handled by the sophisticated system so you can focus on measuring the functional properties of neurons.

Multiwell form factor with no compromise on data quality

Alpha accelerates your time-to-results without giving up any details

Parallelization does not have to be achieved at the cost of sacrificing data quality. Thanks to CorePlate™ 6W 38/60, the HyperCAM Alpha provides thousands of electrodes per-well that can be arranged in different recording configurations to satisfy any experimental needs. The high statistical quality of the data generated by each well reduces the overall needs of replicates. While also giving access to single-cell details with a spatio-temporal resolution comparable to that provided by our single well CorePlate™.

HyperCAM Alpha with CorePlate™ powered multiwell plate

HyperCAM Alpha view with CorePlate™ powered multiwell plate

Flexibility for your experimental needs

One system, multiple purposes

Regardless of whether you want to record human iPSC-derived neurons, dissociated murine cultures, acute brain and cardiac tissues, complex 3D neuronal assemblies, spheroids or brain organoids, HyperCAM Alpha is an ideal multi-well HD-MEA platform.

HyperCAM Alpha enables long term recordings by providing incubator-like conditions with the chamber closed, as well as offering an open configuration for acute measurement requiring the integration of fluidic systems. In both cases, optical access is guaranteed to always keep your preparations under control.

Smart and simple

A concentration of high-tech solutions to simplify experimental procedures

HyperCAM Alpha is designed to reduce experimental hassles and allows you to fully concentrate on the most important thing: your assay.
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The CorePlate™ multi-well environment is regulated by accurately controlling the temperature, CO_₂ saturation and humidity through the software or even the integrated touchscreen.
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The incubation chamber is water-proof to protect instrument electronics from accidental spill-out.
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The combination with the latest BrainWave software allows to easily visualize and analyze data obtained from CorePlate™.

Resources

Here you can find useful resources for your HyperCAM Alpha

HyperCAM Alpha Brochure HyperCAM Alpha User Guide

CorePlate™ Multi-wells

Discover more →

BrainWave 5

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Tech specs

Signal Acquisition Module

Computational core

Intel®’s Arria® 10 FPGA 13Gbps, 4GB DDR4,
and ARM® dual-core Cortex™-A9 1.5 GHz

HD-MEA compatibility

CorePlate™ 6W 38/60

3D HD-MEA compatibility

CorePlate™ 6W-3D 38/60/90

Max number of simultaneous recording wells

Number of simultaneous recording channels

13 824 (2 304 per well) @10kHz
or 6 144 (1 024 per well) @20kHz

Data resolution

14 bit

Electrode subset recording

Yes, predefined regions

Max sampling frequency

20 kHz

Stimulation Module

Stimulus generator

Integrated current stimulator

Number of independent stimulation channels

Real-time adaptive stimulation

Internal (on-chip) Stimulation sites

24,576 (4,096 per well)

External stimulation sites

Maximum amplitude

+/- 1 mA

Amplitude resolution

10 µA

Time resolution

10 µs

Physical specifications

Power supply requirements

100-240 VAC, 50/60 Hz, 2A

Body material

PUR and anodized aluminum for the environmental chamber

Dimensions (W × D × H)

417 mm × 248 mm × 158 mm
(16.4 in × 9.8 in × 6.2 in)

Weight

10.0 kg (22.0 lbs)

Gross weight (with box, accessories)

18.0 kg (39.9 lbs)

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Multi-well system: A new frontier in functional imaging

Overview

Your companion in functional cell screening

Multiwell form factor with no compromise on data quality

Alpha accelerates your time-to-results without giving up any details

Flexibility for your experimental needs

One system, multiple purposes

Smart and simple

A concentration of high-tech solutions to simplify experimental procedures

Resources

CorePlate™ Multi-wells

BrainWave 5

Tech specs

Signal Acquisition Module

Stimulation Module

Physical specifications

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