3Brain's HyperCam Delta logo
The first 24-well HD-MEA platform capable of simultaneous recording from all wells and electrodes

Simultaneous recording of ALL wells, and ALL electrodes

Rat Primary Cortical Neuronal Culture 24 DIV
OVERVIEW
Built with progression in mind, anticipating future demands.    
The system is designed for scalability, supporting robotic automation. The HyperCAM Delta allows you to further expand your research capacity as needed, ensuring you can maximize data collection and streamline your research processes, both now and in the future. 
Obtain more data, more efficiently without compromising quality.
The HyperCAM Delta is a truly unique multi-well HD-MEA platform. With the highest number of simultaneous recording wells and electrodes available on the market, the system enables you to generate high-quality, high-resolution data with exceptional statistical strength. Reducing the need for excessive replicates, accelerating results, and enhancing cost-efficiency throughout your workflow.
High throughput, high accuracy functional screening of your electrogenic cells.

Combined with revolutionary CorePlate™. The HyperCAM delta offers unmatched High DensityMulti Electrode Array (HD-MEA) recording in a 24 well format, with the capability to record from ALL 24 wells and ALL electrodes simultaneously. With its ability to capture data from 24,576 electrodes across all wells at once (1,024 per well), the HyperCAM Delta enables you to gather vast amounts of data from your valuable experiments more efficiently. In addition to this, the HyperCAM Delta features an inbuilt environmental chamber and is automation compliant, further streamlining your workflow. When paired with BrainWave software, the HyperCAM Delta allows for easy navigation and analysis of your large data sets. The efficiency of data collection combined with the ease of analysis make the HyperCAM Delta the ideal choice for your multi-well HD-MEA needs.

KEY FEATURES & BENEFITS
Maximize your Research
The HyperCAM Delta is a cutting edge system with adaptability and scalability at its core. It supports automation, enhancing your labs efficieny and ensuring long term support for your growing research needs.
Simultaneous Recording
In its 24 well format, the HyperCAM Delta offers simultaneous recording from ALL wells and ALL electrodes, the highest amount currently available on the market. This ensures you obtain fast, precise and accurate data from your valuable cultures, spheroids and organoids.
Ensuring High Levels of Reproducibility

With an integrated environmental chamber, you can ensure your samples are being recorded from whilst in their optimum environment, ensuring high levels of reproducibility.

High-Throughput Research

The HyperCAM Delta supports high-throughput research, with its 24 well  CorePlate™.  You can accelerate your research without sacrificing the amount, or quality of data that you would obtain with a single well HD-MEA. Providing the ideal platform to conduct efficient high-throughput screening of your neuronal and cardiac 2D & 3D cultures, spheroids & organoids.

Effortless Analysis

User-friendly analysis tools - saving you time and allowing you to create useful data with ease 

Tailored to your Research Needs

When paired with Brainwave, you can utilize the user friendly analysis tools to navigate your data and generate insightful outputs. With hundreds of metrics available you’ll have the flexibility to create meaningful data, tailored to your research needs.

APPLICATIONS
The HyperCAM Delta is designed for a wide range of applications.
Record from
Primary cultures
HiPSC derived cultures
Spheroids
Organoids
To perform
Toxicology assays
Disease model characterization
Safety pharmacology
Drug screening
DATA EXAMPLES
Primary Neuronal Culture
Hippocampal Culture 17 DIV
Rat Hippocampal Culture 17 DIV showing  a. Raw signal map (change in µV in a 100ms window).  b. Activity map showing Mean Firing Rate (spikes / s)
Raw signal trace showing burst activity, with spikes identified below (white vertical lines) and a detected burst (horizontal yellow line).
Raster Plot showing synchronized activity throughout a Rat Hippocampal Culture at 17 DIV.
Hippocampal Culture 11 DIV
a. Rat Hippocampal Culture at 11 DIV over CorePlateTM. b.Magnification of a central area of the culture. c.Activity map measured by changes in µV in a 100ms window. d. Overlay of the activity map over the culture image.
Spheroids
Human Derived Cortical Spheroids 45 DIV

Spiking activity map (spikes / s) and associated raw trace of human derived cortical spheroids 45 DIV

Cardiomyocyte Culture
Cardiomyocyte Culture 9 DIV
Raw trace from a cardiomyocyte culture 9 DIV displaying a clear initial QRS complex followed by a T wave.
Explore more
Our scientific approach
Publications
Quick access to product families
Multiwell
Single-well
Software
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Events

Tech specs

Main Controller

Compatible with

CorePlate™ 24W

Number of simultaneous recording channels

24,576 (1,024 per well) @10kHz

Environmental chamber

With controlled temperature and CO₂ 
concentration  (via integrated air mixer) 
and with monitored humidity

Data interface

USB 3.1 Type-C data interface

Control software compatibility

BrainWave 5 or higher

Physical specs

Body material

Plastic

Chamber lid

Movable lid with transparent window that
can be operated either by the software or
manually

Locking mechanism

Motorized CorePlate™ locking system

Protection from liquid spill over

Chamber protected against dripping water

Dimensions
(W x D x H)

530 x 290 x 350 mm

Weight

28 Kg

3Brain's HyperCAM Delta logo

The first 24-well HD-MEA platform capable of simultaneous recording from all wells and electrodes

Simultaneous recording of ALL wells, and ALL electrodes

Rat Primary Cortical Neuronal Culture 24 DIV

OVERVIEW
Built with progression in mind, anticipating future demands.     
The system is designed for scalability, supporting robotic automation. The HyperCAM Delta allows you to further expand your research capacity as needed, ensuring you can maximize data collection and streamline your research processes, both now and in the future. 
Obtain more data, more efficiently without compromising quality.
The HyperCAM Delta is a truly unique multi-well HD-MEA platform. With the highest number of simultaneous recording wells and electrodes available on the market, the system enables you to generate high-quality, high-resolution data with exceptional statistical strength. Reducing the need for excessive replicates, accelerating results, and enhancing cost-efficiency throughout your workflow.
High throughput, high accuracy functional screening of your electrogenic cells.
Combined with revolutionary CorePlate™, the HyperCAM Delta offers unmatched High Density Multi Electrode Array (HD-MEA) recording in a 24 well format, with the capability to record from ALL 24 wells and ALL electrodes simultaneously. With its ability to capture data from 24,576 electrodes across all wells at once (1,024 per well), the HyperCAM Delta enables you to gather vast amounts of data from your valuable experiments more efficiently. In addition to this, the HyperCAM Delta features an inbuilt environmental chamber and is automation compliant, further streamlining your workflow. When paired with BrainWave software, the HyperCAM Delta allows for easy navigation and analysis of your large data sets. The efficiency of data collection combined with the ease of analysis make the HyperCAM Delta the ideal choice for your multi-well HD-MEA needs.
KEY FEATURES & BENEFITS
Maximize your Research
The HyperCAM Delta is a cutting edge system with adaptability and scalability at its core. It supports automation, enhancing your labs efficieny and ensuring long term support for your growing research needs.
Simultaneous Recording
In its 24 well format, the HyperCAM Delta offers simultaneous recording from ALL wells and ALL electrodes, the highest amount currently available on the market. This ensures you obtain fast, precise and accurate data from your valuable cultures, spheroids and organoids.
Closer look at 3Brain's HyperCAM Delta sample chamber.
A close up image of the CorePlate™ sitting in the HyperCAM Delta's sample chamber.
Ensuring High Levels of Reproducibility
With an integrated environmental chamber, you can ensure your samples are being recorded from whilst in their optimum environment, ensuring high levels of reproducibility.
High-Throughput Research
The HyperCAM Delta supports high-throughput research, with its 24 well CorePlate™. You can accelerate your research without sacrificing the amount, or quality of data that you would obtain with a single well HD-MEA, providing the ideal platform to conduct efficient high-throughput screening of your neuronal and cardiac cultures, spheroids & organoids.
Effortless Analysis
User-friendly analysis tools - saving you time and allowing you to create useful data with ease. 
Tailored to your Research Needs
When paired with Brainwave, you can utilize the user friendly analysis tools to navigate your data and generate insightful outputs. With hundreds of metrics available you will have the flexibility to create meaningful data, tailored to your research needs.
A computer screen that shows a complex data visualization interface with 3Brain’s Brainwave software.
APPLICATIONS
The HyperCAM Delta is designed for a wide range of applications.
Record from
An icon for primiary cultures.
Primary cultures 
An icon for HiPSC derived cultures.
HiPSC derived cultures
An icon for Spheroids.
Spheroids
An icon for Organoids.
Organoids
To perform
An icon for disease model characterization.
Toxicology assays
An icon for disease model characterization.
Disease model characterization
An icon showing drug screening.
Drug screening
An icon showing safety pharmacoogy.
Safety pharmacology
DATA EXAMPLES
Primary Neuronal Culture
Hippocampal Culture 17 DIV
This image represents a visual data analysis of neural activity captured via a multi-electrode array (MEA) system, used in electrophysiology research. The image contains four main sections, each labeled (a, b, c, d) and connected to a multi-well plate on the left side of the image.
Rat Hippocampal Culture 17 DIV showing a. Activity map showing Mean Firing Rate (spikes / s). b. Raw signal map (change in µV in a 100ms window).
c. Raw signal trace showing burst activity, with spikes identified below (white vertical lines) and a detected burst (horizontal yellow line). d. Raster Plot showing synchronized activity throughout a Rat Hippocampal Culture at 17 DIV.
Rat Hippocampal Culture 17 DIV showing  a. Raw signal map (change in µV in a 100ms window).  b. Activity map showing Mean Firing Rate (spikes / s),
Raw signal trace showing burst activity, with spikes identified below (white vertical lines) and a detected burst (horizontal yellow line).
Raster Plot showing synchronized activity throughout a Rat Hippocampal Culture at 17 DIV.
Hippocampal Culture 11 DIV

a. Rat Hippocampal Culture at 11 DIV over CorePlateTM. b. Magnification of a central area of the culture. c. Activity map measured by changes in µV in a 100ms window. d. Overlay of the activity map over the culture image.

Spheroids
Human Derived Cortical Spheroids 45 DIV

Spiking activity map (spikes / s) and associated raw trace of human derived cortical spheroids 45 DIV

Cardiomyocyte Culture
Cardiomyocyte Culture 9 DIV
Raw trace from a cardiomyocyte culture 9 DIV displaying a clear initial QRS complex followed by a T wave.
See more about our MEA neuro-imaging technology in action
Video Gallery
Resources for HyperCAM Delta
Download Brochure

Tech specs

Main Controller

Compatible with

CorePlate™ 24W

Number of simultaneous recording channels

24,576 (1,024 per well) @10kHz

Environmental chamber

With controlled temperature and CO₂ 
concentration  (via integrated air mixer) 
and with monitored humidity

Data interface

USB 3.1 Type-C data interface

Control software compatibility

BrainWave 5 or higher

Physical specs

Body material

Plastic

Chamber lid

Movable lid with transparent window that
can be operated either by the software or
manually

Locking mechanism

Motorized CorePlate™ locking system

Protection from liquid spill over

Chamber protected against dripping water

Dimensions (W x D x H)

530 x 290 x 350 mm

Weight

28 Kg

Do you want to know more?
Book a chat or email us, as our neuroscientist team is here to assist you.
Contact Us